If we are to garner sustained U.S. domestic support for future trade agreements, we have to make sure those Americans who have suffered as a consequence of past agreements have an effective social safety net, adjustment assistance, opportunities for retraining and new job creation that enables all Americans to thrive.

Legislation that would withhold funding for the United Nations is fundamentally flawed in concept and practice, sets us back, is self-defeating, and doesn't work.

Our bottom line, if you want to call it a red line, president's bottom line has been that Iran will not acquire a nuclear weapon and we will take no option off the table to ensure that it does not acquire a nuclear weapon, including the military option.

There was a hateful video that was disseminated on the internet. It had nothing to do with the United States government and it's one that we find disgusting and reprehensible. It's been offensive to many, many people around the world.

We must be honest in acknowledging that neither Germany nor the U.S. has the luxury of assuming that we can skate by on half-measures in Afghanistan and Pakistan and not risk suffering the consequences.

Well, I think by any expectation South Africa has come a tremendously long way. We've seen a society that many people thought couldn't withstand a peaceful transition to democracy without a great deal of violence, in fact, make that transition and do it in relative peace and security.

Well, Nigeria has played a constructive role in peacekeeping in various parts of West Africa. But unless and until Nigeria itself is democratic and respects human rights, it too may well be a source of much greater instability as political repression limits the ability of the people of Nigeria to achieve their full potential.

I am a team player - and that is what you need to be an effective point guard. You gotta see the court, you gotta set up the play, and you gotta let others execute for the most part. I don't throw elbows for the sake of throwing elbows, but if somebody throws one at me and it's necessary to respond in kind, I suppose I can if I have to.

Americans are hungry for change both at home and in our relations with the rest of the world.

Americans understand that our security is enhanced when the United States is trusted and respected in the world.

I am a direct person.

I am very aware of being black and female because that's what I am.

I have been to Libya and walked the streets of Benghazi myself.

I spend every day up at the United Nations where I have to interact with 192 other countries. I know how well the United States is viewed.

I think most Americans understand that we went through a period in which American leadership was judged quite critically internationally.

I was conscious of the fact that it could be to my disadvantage to marry a white guy - that some folks would hold that against me.

I would rather be alone and a loud voice for action than be silent.

In this day and age, the U.S. and Europe do not have the luxury of focusing solely on a single region.

Iran's economy is now shrinking by 1 percent a year. Its oil production is down 40 percent.

My kids have been incredibly supportive of the work that I do. They understand why it matters.